What is the correct route and dose for administering Ketamine for sedation?

The appropriate route and dose for administering Ketamine for sedation is to give 20-30 mg via slow intravenous (IV) or intraosseous (IO) administration. This dosing range is effective in producing sedation quickly and is well-established in both pre-hospital and hospital settings.

Slow IV or IO administration is crucial for managing the rapid onset of sedation, which is particularly important in tactical environments where patient stability and safety are paramount. Within this dosing range, Ketamine typically provides a good balance of sedation and analgesia while minimizing the risk of adverse effects commonly associated with higher doses.

In contrast, smaller doses may not achieve the intended level of sedation, while larger doses, such as those in the other options, could lead to prolonged sedation or potential respiratory compromise. This makes 20-30 mg via slow IV/IO the safest and most effective choice for rapid and reliable sedation in tactical situations.