What is the shelf-life of cold-stored low-titer O whole blood (LTOWB)?

The shelf-life of cold-stored low-titer O whole blood (LTOWB) is specifically recognized to be 21 or 35 days, depending on the storage conditions and blood bank practices. This product is utilized in various military and trauma settings due to its safety profile and availability for emergency transfusions, particularly in mass casualty situations.

Low-titer O whole blood is derived from donors who have a low antibody titer against A and B antigens, which minimizes the risk of hemolytic transfusion reactions, making it especially suitable for group O patients. The storage conditions—typically between 1 to 6 degrees Celsius—are critical, and the shelf-life can vary based on the presence of specific additives in the blood product that may extend its viability.

Thus, understanding the appropriate shelf-life of LTOWB is crucial for ensuring the blood remains safe and effective for transfusion when needed. This information is vital for medical personnel to manage blood resources effectively, particularly in tactical and emergency conditions where time and blood compatibility can significantly impact patient outcomes.